Biography:

man Tourbah, MD, PhD, is a Neurologist and Neuroscientist (Paris VI). A Professor of Neurology, he is responsible for the MS Center at the University Hospital of Rheims, France. His main areas of research are MS, neuro-ophthalmology, neuro-metabolic diseases and MRI. He published more than 100 original articles and participates in many phase II and III clinical and MRI studies in MS, and recently coordinated two phase III trials studying the effect of high doses of biotin in patients with MS. He is a Member of the MS Experts’ Panel of the EAN, and the Coordinator of the LSN MS guidelines.

Abstract:

Progressive multiple sclerosis (MS) is characterized by the accumulation of disability over time that may follow a period of clinical relapses (secondary progressive MS) or appear since onset (primary progressive MS). Current therapeutical strategies are based on immunotherapies that may delay disability progression. No approved treatment has clearly demonstrated efficacy on the neurodegenerative component of the disease. Future strategies are studying the possibility of enhancing endogenous or exogenous remyelination, and presumed neuroprotective properties of anti-epileptic, anti-arrhythmic and anti-glutamatergic drugs, among others. We recently demonstrated that MD1003 (high doses of biotin, MedDay Pharmaceuticals, Paris, France) was able to reverse disease progression in patients with progressive not active MS, with a maintained efficacy over 2 years, and a good tolerance of the treatment. MD1003 may act as a neuroprotective agent, increasing energy supply and thus reversing virtual hypoxia that is present in progressive MS. It may also promote remyelination by activating intra-oligodendroglial lipid synthesis. Thus, targeting neuronal and oligodendroglial metabolism represents a promising perspective in treating patients with progressive MS.

Biography:

Gunel Zeynalova-Latifofa, has graduated at the age of 22years from Azerbaijan Medical University. She has practiced as an assistant of the Professor of Child Neurology Z.Aliev during 5years. Then she has worked as an child Neurology doctor in Child Neurology Center in Baku. In 2014 she has taken EEQ course in Neurophysiology University in Moscow, in Pediatrics University in Moscow, in Neurology University in Moscow during 2month. She has some certificates’ from World Neurology Congresses. She is working as a chief doctor in private hospital named by Medicus Klinika.

Abstract:

Nonepileptic paroxysmal disorders in children and adolescents is a large group of diseases and syndromes, which are characterized by relatively sporadic loss of consciousness and/or diverse motor, emotional, psychological vegetative problems. In broad sense of the concept N.E.P.R. includes any suddenly appeared symptoms for which the term "epilepsy" is not suitable.

1. Syncopal states - syncope, fainting, collapse.

2. Non epileptic sleep disorders.

3. Disorders related to impairment in emotional spheres (panic attacks, bouts of hysteria)

4. Other childhood paroxysmal disorders (affective-respiratory paroxysms, fading (starring), grimace, trembling attacks, masturbation in young children, muscle spasms while chewing).

5. Extrapyramidal symptoms

6. Migraine.

7. Somatogen paroxysmal disorders.

8. Paroxysmal disorders with acute cerebral blood circulation with traumatic brain injury etc.

The ILAE 2001 8th section includes seizures, for which the definition of "epilepsy" is not always suitable. This group can also contain the following disorders:Benign neonatal seizure, Febrile seizures, Reflex seizures, Seizures associated with alcohol withdrawal, Seizures associated with taking different medicines etc.

Affective-respiratory paroxysms occur in young children in response to exogenous adverse impacts. The frequency of the disease in the pediatric population comprises 4-17% .Given that affective-respiratory paroxysms are accompanied by apnea and/or asystole and many authors consider them to be life endangered state. According to some data, affective-respiratory paroxysms amount for about 8% of such states.

The causes and mechanisms of the emergence of the disease.

Affective-respiratory paroxysms are initiating paroxysms. For the activation of the disease there must be the impact of some factors causing dissatisfaction, anger, fear or pain. Each child can have a special practical factor. As a result, there is a strong cry, where hyperventilation of lungs, hypocapnic ischemia of the brain and low blood pressure problems take place.

Weeping causes the spasm of the respiratory tract and as a result the mechanism Valsalva Weber is triggered, when due to the rise in thoracic pressure, venous return to the heart and cardiac output as well as minute volume of blood stream decrease, which leads to hypoperfusion of cerebral arteries and simultaneously to venous stasis. In combination with hypoxemia it results to the loss of consciousness and/or convulsions. This gives diffuse cyanosis of the skin, i.e. cyanotic affective-respiratory paroxysms.

Sometimes “pale” affective-respiratory paroxysms can take place, where the initiating agent is either pain or fear. It is short-term state, where asystole takes 10 seconds, sometimes 20 seconds. Thus, the main pathogenetic link in the affective-respiratory paroxysms is apnea or apnea + asystole.

It is clear that apnea does not have central origin, as respiratory efforts and the motion of respiratory muscles are observed in the absence of air stream in the upper respiratory tract. If a child has epi center or epi activity it can lead to the epi seizures.

Anemia may contribute to an increase in the degree of hypoxia.

Usually children with affective-respiratory paroxysms grow up either in socially unfavorable families or in "overprotection" conditions. But typically if it does not result in the epi, the intellectual and mental development is normal. The affective-respiratory paroxysms can last till 6 years old and it reaches its peak at the age of 6-18 months old. The frequency of several attacks per hour may account for 1 attack per month, but during intercurrent diseases it quickens. 

Biography:

M B Evgenev has completed his PhD from Institute of Developmental Biology, Moscow, Russia. He was Professor of Biology in 1990. He spent ten years in USA as Visiting Professor (U of John Hopkins, Baltimore, U of Arizona and Chicago University within 1990-2000 time period). He is Head of Laboratory of Molecular Basis of Biological Adaptation in Engelhardt Institute of Molecular Biology. He has published more than 140 papers in reputed journals and has been serving as an Editorial Board Member of repute in several journals.

Abstract:

Alzheimer’s disease (AD) is the most prevalent neurodegenerative pathology in the growing population of elderly humans and leads eventually to dementia and death. Despite tremendous efforts, no effective treatment for AD is currently available. Molecular chaperone Hsp70 plays protective role in various neurodegenerative disorders. Various data suggest that Hsp70 and other molecular chaperones function as a complex neuroprotective system, which fails in the brains of aged people and AD patients. In special experiments, we demonstrated that eHsp70 effectively crosses the blood-brain barrier when administered intranasally. Here we have shown that chronic administration of exogenous Hsp70 (eHsp70) decreased beta-amyloid level and preserved neuron density in two mouse models of Alzheimer disease. In both cases eHsp70 restored behavior and memory disturbed by Alzheimer disease and aging.  We also explored the effect of eHsp70 on neurons morphology and survival in the cortex and the hippocampus of transgenic animals. The proportion of pathologic neurons decreased drastically in Hsp70-treated animals. Therefore, Hsp70 treatment of model mice protects neurons from deterioration and death in brain areas most affected in AD patients. In conclusion, we can summarize that the intranasal administration of recombinant human Hsp70 drastically alleviates all symptoms, including memory loss, neuronal death, cellular aberrations and accumulation of the Aβ-peptide in both AD-models explored. Deep sequencing studies enabled to reveal candidate genes and signal pathways underlying beneficial effects of eHsp70 treatment. In our experiments we also demonstrated that intranasal administration of exogenous recombinant human Hsp70 can promote longevity in male but not female mice. The Hsp70 treatment also normalized the synthesis of synaptophysin in aged mice and decreased accumulation of lipofuscin which represents the marker of aging and neurodegeneration processes. Taken together, our findings establish exogenous human Hsp70 as a practical pharmacological agent for the treatment of various neurodegenerative diseases and aging.

Biography:

Sevinj Hamidova Abisalam graduated with MD from Azerbaijan Medical University in 2009. She then completed Internship in City Clinical Hospital in Baku and has now worked for over 6 years as a Neurologist at several hospital settings. During this period, she has participated in many conferences and has taken several continuing education neurology courses in Turkey, Germany, Spain and Denmark. She is well skilled and has managed headache, stroke, epilepsy/EEG and prolotherapy protocols. She organized and now directs a small Headache Center in Baku. At present, she is tasked to organize a Stroke Center–a first in Azerbaijan, and has been offered a new job in one of the big private clinics in Baku as a Director of Stroke and Headache Center.

Abstract:

Chronic migraine (CM) is a major global health problem in need of an effective prophylactic treatment with minimal side effects. And the purpose of this study was to compare the efficacy and safety of onabotulinumtoxin A with topiramate (Topamax), amitriptyline, and candesartan (Onsart) prophylactic treatments in CM. A total of 170 subjects with CM- comprising of four groups–received: Group 1) onabotulinumtoxin A, max 200 units (U) at baseline and month 3; group 2) topiramate (Topamax), 4 weeks titration 100 mg/day; group 3) amitriptyline, 3 months titration, 25 mg/day; and group 4) candesartan (Onsart), 16 mg/day. In all the treatment groups, control groups received oral placebo or placebo saline injections. Treatment responder rates were assessed using Physical Global Assessment 9-point scale, including the change from baseline in the number of headache (HA/migraine/day per month); disability was measured using Headache Impact Test (HIT-6), and Migraine Disability Assessments. The overall study duration was about 9 months. Of the 170 patients (mean age, 34.4 +/-10.6 years; 95% female), 117 completed the study at the end of the 7 months of active treatment: Onabotulinumtoxin A, n=24, topiramate (Topamax), n=37; amitriptyline, n=30; and candesartan (Onsart), n=17. Almost all patients in all treatment groups reported moderate to marked improvements at all points. But 26% in topiramate group, 28% in amitriptyline group and 23% in candesartan group reported adverse effects that required discontinuation of treatment compared to only 3.1% of patients in the onabotulinumtoxin A group. Onabotulinumtoxin A is as effective for treatment in CM as the other migraine prophylactic drugs with much less side effects.

Biography:

Swarupa Mitra has served as a Consultant, Faculty, and as Research Guide to post graduate students since 2000. She has many publications in international journals and has several research projects to her credit, including the prestigious one with the National Cancer Registry Program where she is the Principal Investigator. She has authored books and has been a Reviewer in some international journals. She is the Nominated Member of the Project Advisory Board by Department of Science and technology, Government of India.

Abstract:

Brain metastases constitute approximately 15%-30% of all intracranial tumors. As much as 30% of patients will develop brain metastases as a part of their primary cancer. Whole brain radiotherapy (WBRT), with or without SRS boost is the mainstay in the treatment of brain metastases. While, there has been an improvement in the median survival, with a significant decline in the risk of recurrence and in the risk of neurological death, a paradoxical reduction in neurocognitive functions (NCF) appears as a sequel and which cannot be neglected. This impairment starts within 1-4 months of the WBRT. The sub-granular zone of the hippocampus that contains proliferating neuronal progenitor cells is an integral component of memory formation and learning. Following WBRT, the decline in the neurocognitive functions may be due to radiation induced impairment in hippocampal neurogenesis. Mean doses of 45 Gy or higher to the left temporal lobes are associated with significant decline in the IQ. Biologically equivalent dose greater than 7.3 Gy applied to 40% of hippocampal volume may cause long-term impairment in neurocognitive functions. With improvements in imaging and its incorporation in conformal radiotherapy planning, it is now possible to selectively spare the hippocampus from radiation and improve the quality of life and NCF of patients. Neurocognitive sparing radiotherapy promises to prove as a novel mode for ensuring the efficacy of WBRT while minimizing its associated neurocognitive dysfunctions.

Biography:

Baris Cankaya graduated from Ankara University Medical Faculty in 2000. He has been working as Anesthesiology specialist at Marmara University Training Hospital. He has attended academic meetings nationally and internationally. His academic interest includes microcirculation, fluid therapy, resuscitation, patient safety and peri-operative analgesia.

Abstract:

Interventional neuroendovascular procedures have a larger percentage day by day. Comparing with surgery it has advantages for blood loss, length of stay in hospital and shorter time. But it has well-known complications such as ischemis, hemorrhage and bradycardia. The procedure is performed outside operating room in radiology unit, mainly. Additional to peripheral pulse oxymeter, the operating team will have additional parameter by monitoring cerebral oxygenation as regional monitoring for detecting early complications. Neurologic complications of cerebral angiography are reported to occur in 1% to 14% of cases. Common complications are permanent or transient neurologic deficits related to thrombus, embolism, vasospasm, air embolism, arterial occlusion and contrast induced nephropathy, lactic acidosis, contrast allergy and vessel rupture. Cerebral optical spectroscopy is a non-invasive technique and provides real-time results. This technique uses near-infrared light to supply physiologic information about the brain tissue and performs thorough preoperative evaluation and planning. We have to minimize the risk of the complications by focusing on patients with a high atherosclerotic disease, diabetes, chronic renal insufficiency. One-sided alterations on cerebral oxymeter give us early information about post-procedural neurologic outcome. The interventionist may change the decision for stent or coil placement according to these alterations. In case of balloon inflating, bradycardia may develop and the decision for atropine is made hardly if the beat-perm in is between 45 and 55. We can also get help from cerebral oxymeter if desaturation occurs or not for bradycardia.

Biography:

Ahmed Al Jishi graduated from Arabian Gulf Neurosurgery, Bahrain and completed his Neurosurgery Training at McGill University, Montreal in 2012. On completion of training, he further completed Fellowships in Pediatric Neurosurgery and Spine Neurosurgery. He is recognized by the Royal College of Physicians and Surgeon in Canada. He is currently a practicing Neurosurgeon with Hamilton Heath Sciences where he also carries the Lead on the Neuromodulation Program for pain and spasticity. He published many papers in professional journals and has been an active participant in international conferences. His particular interests are in neuro-oncology, functional neurosurgery and spine research.

Abstract:

Introduction: Placement of an EVD is one of the most common ICU procedures that the neurosurgery residents practice at early stage of training. The safe use of such tool demands adherence to specific anatomical landmarks and procedure-related guidelines so as to avoid the certain pitfalls. It is valuable therefore that training programs periodically revisit their training in relation to outcomes in order to minimize problems and maximize training and clinical safety.

Methodology: The data were retrieved for patients admitted with an aneurysmal SAH to the Montreal Neurological Hospital and Institute between July 2006 and May 2009. We included all EVDs that were planned for frontal horn. The adequacy of EVD insertion, encountering vital anatomical structures, complications and resident’s level of training were analyzed based on the grading scheme.

Results: Around 160 EVDs were inserted in the ICU after intracranial bleeding. Of those 15.7% landed in optimum intraventricular zone “foramen of Monro” (grade I) and 47.6% landed in the third or lateral ventricles (grade II) while 36.7% had a remote landing in parenchyma or CSF space (grade III). The latter was associated with a higher risk for complications.

Conclusion: The practice of EVD insertion, based on external surface landmarks, is associated with a high risk of missing the intended intraventricular target and potential serious complications. The proposed grading system for EVD insertion can be a useful assessment tool to evaluate out practice but further testing is required prior to validation.

Biography:

Aguinaldo Pereira Catanoce is Graduate and Post-graduate in Medicine and Neurosurgery from the Catholic University of Campinas in Brazil. He is Member of the Brazilian Society of Neurosurgery since, 2009. He has 8 years of neurosurgery experience in video endoscopes for brain tumors at the base of skull and intraventricular area in addition to the improvement of microsurgical treatment of vascular lesions. He is Neurosurgeon Professor in the discipline of Neurosurgery at the University of Campinas, Brazil, since 2011 and Manager Medical and Technical Director of University Hospital, São Paulo, Brazil, with experience in hospital management of 7 years.

Abstract:

Held important development with the description and improvement of surgical treatment of pituitary tumor through video-endoscopic technique. The technique describes the endoscopic fully endonasal transsphenoidal surgery for pituitary tumors. A series (over 120 cases) of procedures, over last 7 years, in a University of Campinas and University Hospitals in Brazil was done. It described statistics biochemical, clinical and radiologic results with a specific radiologic pre- and post-operative image. An angiotopographic bone study for sphenoid sinus details and magnetic brain image is used. In the fully endonasal endoscopic technique, we encountered less morbidity/mortality statistics and more patient satisfaction. The advancements of fully endoscopic endonasal surgery of pituitary adenomas led to a better endocrinologic clinical and radiologic control, and less morbidity.

Biography:

Aguinaldo Pereira Catanoce is Graduate and Post-graduate in Medicine and Neurosurgery from the Catholic University of Campinas in Brazil. He is Member of the Brazilian Society of Neurosurgery since, 2009. He has 8 years of neurosurgery experience in video endoscopes for brain tumors at the base of skull and intraventricular area in addition to the improvement of microsurgical treatment of vascular lesions. He is Neurosurgeon Professor in the discipline of Neurosurgery at the University of Campinas, Brazil, since 2011 and Manager Medical and Technical Director of University Hospital, São Paulo, Brazil, with experience in hospital management of 7 years.

Abstract:

Development and improvement of multidisciplinary work in the treatment of major vascular lesions of the nervous system. Implemented a corporative hospital management system and clinical care aimed at the fast and efficient service in cases of hemorrhagic stroke, especially of the cerebral aneurysm. Feasibility of endovascular or surgical tratament. Described and documented the efficiency and the good results through the organization of medical and multidisciplinary team associated with the corporate organization focused on innovation in the management model.

Biography:

Suad Alanzi has completed her PhD in 2011 from Curtin University and Post-doctoral studies from different institutes. She is the founder of Developmental Coordination Disorder Clinic in Kuwait, a co-coordinator of CP clinic in Sabah hospital and a head of Risk analysis Committee and active member of risk management committee. She has presented more than 15 papers in international conferences and has been serving as a reviewer member of Journals and conferences. Furthermore, she conducted several postgraduate workshops in the field of pediatric, evidence-based practice and ICF model nationally and internationally.        

Abstract:

According to DSM-V, children with developmental coordination disorder (DCD) have motor coordination impairments and their motor abilities are substantially below their age and intelligence levels. The motor impairments are not due to medical or neurological disorder. Their motor difficulties negatively influence their life and cause medical and psychosocial problems. Identifying DCD and measuring its prevalence in society requires applying the inclusion and exclusion criteria. Therefore, ignoring one or more of these criteria would bias the results. There are many factors impact on the accuracy of diagnosing DCD like using valid assessment tools, reliable neurological examination, and co-morbidity with other disorders. Applying criteria A and B of the DSM-V requires valid standard assessment tools. A consultation held by the WHO reviewed several assessments of child development and found that not all the assessments were suitable for use in different cultures or in similar cultures with different societies. It was suggested that when using child development assessment or screening tools each country should have its own normative data. The DSM-V exclusion criterion is to exclude neurological disorders. However, not all children with minimal brain dysfunction due to low birth weight (LBW) and/or small for gestational age (SGA) show clear neurological problems that require examination or have been given a neurological disorder diagnosis. Therefore, children with mild Cerebral Palsy (CP) might be misdiagnosed with DCD. Furthermore, DCD overlaps with other developmental disorders like ADHD, LD, Autism, and SLD because of sharing etiology and/or symptoms. Their relations could be co-morbidity, co-occurrence or continuum. 

Biography:

Nadežda Lukáčová, DSc, is Head of Laboratory of Neurochemistry and Neurophysiology at the Institute of Neurobiology, Slovak Academy of Sciences. Her research focuses on the role of signaling molecules in the brain and spinal cord circuitry under physiological and pathological conditions. She has published more than 80 papers in peer-reviewed journals. Currently, she is a Garant of ongoing accredited program of doctoral studies in the field of Animal Physiology. She is experienced in the project management within both, national and international grant schemes.

Abstract:

Acute traumatic spinal cord injury (SCI) causes significant neuropathological deficits with limited regeneration, depending on the degree of neuronal tissue destruction. Our study was aimed to i) characterize a preclinical model of SCI (8N, 15N and 18N force) at L3 level in minipig using computer-controlled compression apparatus, ii) optimize conditions of local cooling of the spinal cord at the site of injury, and iii) to find out whether hypothermia applied at defined temperature (for 5 h) will have beneficial effect on the gray and white matter sparing, the number of neurofilaments and neurological outcome. Hypothermia was performed locally through perfusion chamber with 4°C saline solution perfusion, oxygenated culture medium or enriched medium. The animals were behaviorally assessed during 9 weeks of survival. We have found that saline hypothermia leads to a gray and white matter sparing, and to substantial sparing of neurofilaments in segments away (rostrally +3, +2, +1 and caudally -1, -2, -3) from the lesion site, i.e. in spinal cord sections that are likely to be affected by secondary injury. In particular, we have shown that saline hypothermia after 8N SCI, causing the sparing of axons in lateral funiculi at +1 and -1 (improvement by 25% and 19%), showed favorable neurological outcomes. Such improvements were not observed in the group subjected to more severe SCI. The application of local hypothermia in computer-controlled minipig compression model provides data analogous to impact of such treatments in patients. 

Biography:

Ajay Bajaj has done his MCh neurosurgery degree from Postgraduate institute of medical education and research, Chandigarh , India. He had 5 publications in various national and international journals. He also participated in CRASH trial conducted by MRC London. He is an active international member of CNS and executive council member of Neurological surgeon society of India. He had worked as assistant professor of neurosurgery in various medical institutes of India. Presently he is working as consultant Neurosurgeon at Wockhardt hospitals Ltd. Mumbai, India.

Abstract:

Spina bifida is a common congenital anomaly encompassing a wide spectrum of neural tube defects. It is broadly classified as spina bifida aperta and occulta. With the prenatal screening, the incidence of aperta is gradually declining, whereas the detection of occulta has increased with the advent of magnetic resonance imaging.

The estimated incidence of spinal dysraphism is about 1–3/1000 live births. The prevalence of spinal dysraphism has been in decline the world over in the last few decades due to the better nutrition for women, folic acid supplementation, improved antenatal care and high-resolution ultrasound for prenatal screening and biochemical markers.

Open dysraphism presents with a swelling over the back which is noticed at birth. Symptoms are primarily referable to CSF leak or the exposed spinal cord.

Tethered cord syndrome has been defined as progressive neurological deficits from the restraint of the spinal cord movement and traction due to either anatomical or physiological reasons. It may lead to progressive neurological, urological and orthopedic dysfunctions. Tethered cord can be seen in both varieties (Aperta and Occulta) of spinal dysraphism. Approximately 30% of patients present with retethering due to previous myelomeningocoel surgery .

Patients usually presents with neuro-urological symptoms with progressive foot deformity. In our experience, the common clinical presentations include the presence of cutaneous stigmata associated with occult spinal dysraphism (70%), neurogenic bladder with the development of primary or secondary incontinence or urinary tract infection (60%), leg or foot weakness, numbness and/or spasticity (60%%), leg or foot length discrepancy (10%)and foot deformity (for example, pes cavus, claw toes). One of our patients presents as auto amputations of toes of both feet. The neurological dysfunction in tethered cord syndrome is unusual, frequently having elements of both upper and lower motor dysfunction. Motor weakness is more prevalent than sensory deficits. Such motor dysfunction is usually asymmetrical.

The fundamental goals of surgical intervention in spinal dysraphism with tethered cord syndrome are as follows: 1) to improve or stabilize deficits in the symptomatic patient and 2) to prevent future deficits in the asymptomatic patient. These two goals are predicated on the fact that sectioning of the terminal filum can be conducted safely with minimal risk and a very low rate of morbidity. The incidence of neurological injury due to sectioning is less than 1%.

Detethering of the cord is an important part of surgical treatment as the major cause of neurological deterioration in these patients is due to abnormal fixation and traction on the conus and distal cord.

In conclusion, technically, detethering of the cord is not challenging but identification of the patients who will be benefitted with the procedure is really challenging. Therefore, there is a need to continue critically looking at this disease process to obtain better data through randomized prospective studies.

Biography:

Yafa Alshamlan is currently working in the department of neuro-ophthalmic at a tertiary referral hospital, Abdulaziz University Hospital (KAUH) in Riyadh, Saudi Arabia. Yafa Alshamlan has published several original research papers and also participated into the several meetings.

Abstract:

Purpose: To assess the pattern and epidemiological characteristics of neuro-ophthalmic cases presented to ophthalmic Emergency Department (E/D) at a tertiary referral hospital, King Abdulaziz University Hospital (KAUH) in Riyadh, Saudi Arabia from May 2013 to April 2015.

Method: A retrospective study that implied all patients who presented to the ophthalmology E/D from May 2013 to April 2015 at KAUH. Data were collected from ophthalmic emergency registry book for all patients fulfilling the inclusion criteria and were analyzed according to demographics, date of visit, diagnosis and management.

Results: Among the emergency cases that presented to KAUH for two consecutive years, 414 cases were diagnosed as neuro-ophthalmic patients. Mean (SD) age was 38.1(19.0) (ranging from 2 months-88 years). Of them, 93.5% were above 15 years of age, gender was almost equally distributed, with the majority being Saudi citizens. Most of cases (78.3%) had unilateral ocular involvement, while (21.7%) were bilateral. Optic neuritis was the most prevalent diagnosis comprising (22.5%) of neuro-ophthalmic emergencies, leaving (15%) for 6th nerve palsy, (10.9%) 3rd nerve palsy, (8.7%) bilateral optic disc swelling, and (7%) 7th nerve palsy in addition to other causes. Half of the cases were managed via home and appointment advice, home and rest covered (33.3%), (4.1%) had home rest and medical treatment regimen, while few cases equally required admission and referral either for further investigations or advised interventions.

Conclusion: The majority of cases were adults with equal gender distribution, mainly presenting with unilateral ocular involvement. Optic neuritis was the most prevalent diagnosis while the most common management was home and appointment advice. Early detection and referral of neuro-ophthalmic cases would enable delivering the optimal healthcare to such cases.